How to Clean Nursing Shoes Without Damaging the Material (Step-by-Step Guide)

If you’re a nurse, your shoes take a beating—12-hour shifts, spills, long walks, and unsanitary hospital floors. That’s why buying good shoes for nurses is important. But cleaning them incorrectly? That’s even worse.

In this complete guide, you’ll learn how to clean nursing shoes without damaging the material, whether they’re mesh, leather, rubber, or Skechers Go Walks. You’ll also discover smart ways to sanitize, deodorize, and even disinfect secondhand shoes.

Many nurses unintentionally destroy their shoes with harsh chemicals, over-soaking, or improper drying. But you’re about to avoid all that—and keep your shoes looking (and smelling) like new.

Why Proper Cleaning Matters

Cleaning your nursing shoes prevents bacteria buildup, removes odors, and extends their lifespan—keeping you safe and comfortable on the job.

Health & Hygiene

Hospital floors are breeding grounds for bacteria, viruses, and chemicals. When you return home, dirty shoes can carry those same contaminants into your house. Regularly cleaning and sanitizing your nursing shoes reduces the spread of pathogens and helps keep your home and workplace safer.

Odor Prevention

After 10 to 12 hours on your feet, it’s natural for shoes to absorb sweat and develop odors. Bacteria trapped inside the shoe fabric and soles can lead to long-lasting smells. Routine cleaning eliminates the bacteria responsible and keeps your shoes fresher longer.

Shoe Longevity

Proper cleaning also helps protect your investment. Quality nursing shoes can cost a significant amount. Maintaining them helps prevent material breakdown, preserves structure and support, and makes them last longer—ultimately saving you money.

Know Your Shoe Material

Different shoe materials react uniquely to cleaning methods. Before you begin, identify what your nursing shoes are made of.

Common Materials:

• Leather/Faux Leather: Water-resistant but sensitive to over-saturation and heat. Benefits from conditioning.
• Mesh/Fabric: Breathable but can trap dirt. Must be cleaned delicately.
• Synthetic Materials: Durable, but can discolor or wear down with harsh chemicals.
• Rubber Soles: Highly durable, but collect grime and bacteria easily.

Cleaning your shoes starts with knowing what they’re made of—key to learning how to clean nursing shoes without damaging the material.

General Cleaning Method (Step-by-Step)

This universal method works for most shoes unless otherwise specified. Always test on a small area first.

When it comes to maintaining nursing shoes, having a go-to general cleaning routine can make all the difference. This universal method is safe for most shoe types—leather, mesh, synthetic, and rubber—unless otherwise stated. Before diving in, always test your chosen cleaning technique on a small, hidden area to ensure the material reacts well.

To get started, gather a few basic items: a soft brush or an old toothbrush, mild dish soap, warm water, a microfiber cloth, and a dry towel. These gentle tools will help remove dirt and grime without scratching or damaging the material.

What You Need:

• Soft brush or toothbrush
• Mild dish soap
• Warm water
• Microfiber cloth
• Dry towel

Step-by-Step Guide:

1. Remove surface debris: Use a soft brush to remove dried dirt or dust.
2. Create a cleaning solution: Mix warm water and a few drops of dish soap.
3. Spot clean: Dip a cloth into the solution and gently scrub the upper material.
4. Wipe clean: Use a clean, damp cloth to remove soap residue.
5. Dry properly: Pat shoes dry with a towel and let them air dry naturally. Keep away from direct heat.

Begin by removing surface-level debris using the soft brush. Carefully brush away dried mud, dust, or hair from the shoe’s surface and sole. Next, prepare a simple cleaning solution by mixing a few drops of dish soap into a bowl of warm water. Avoid using hot water as it may cause certain materials to warp or degrade.

Dip your microfiber cloth into the soapy water, wring it out to avoid oversaturation, and gently scrub the upper part of your shoes. Focus on areas with visible dirt or stains. For stubborn spots, you can use the toothbrush in small, circular motions to lift grime without damaging the shoe.

Once you’ve finished scrubbing, use a clean damp cloth (soaked in plain water and wrung out) to wipe away any soap residue. This step is essential—leaving soap behind can attract more dirt and potentially degrade the material over time.

Finally, pat the shoes dry with a towel and leave them to air dry naturally. Choose a well-ventilated area away from direct sunlight or heat sources like radiators or dryers, which can cause shrinking, warping, or cracking—especially with leather or synthetic materials.

What to Avoid:

• Do not soak the shoes
• Never use bleach or strong chemicals
• Avoid machine drying

Never soak nursing shoes in water, no matter the material. Excessive moisture can break down adhesives and padding, causing the shoes to lose their shape or structure. Avoid bleach or other harsh cleaning agents, which can discolor or weaken the material. Also, resist the urge to toss them into a dryer—high heat can cause irreversible damage.

By following this simple yet effective process, you’ll maintain the integrity and comfort of your shoes while keeping them clean and professional-looking.

Material-Specific Cleaning Guides

Tailored cleaning methods for leather, mesh, synthetic, and rubber shoes ensure you don’t ruin the material while keeping them spotless.

Leather/Faux Leather

Leather shoes are popular for their sleek appearance and water-resistant properties. However, they are sensitive to moisture and harsh products.

• Wipe the surface gently with a soft damp cloth to remove surface dirt.
• Use a pH-balanced leather cleaner for deeper stains, applied with a microfiber cloth.
• After cleaning, apply a leather conditioner to restore suppleness and prevent cracking or drying.
• Let air dry away from direct heat to preserve shape.

Mesh or Fabric

Mesh and fabric are breathable and flexible, but prone to holding dirt and bacteria.

• Mix warm water with mild laundry detergent or dish soap.
• Use a soft brush (like an old toothbrush) to gently scrub the surface in circles.
• Avoid submerging the shoes completely, as it may damage adhesives or inner lining.
• Use a clean towel to blot moisture and then air dry completely in a well-ventilated area.

Synthetic Materials

Synthetics like polyurethane and vinyl are durable but can degrade with strong chemicals.

• Dampen a cloth with warm water and add a drop of gentle soap.
• Gently wipe down the entire upper.
• Avoid abrasive pads or alcohol-based cleaners that can cause discoloration.
• Dry with a clean towel and leave out to air dry.

Rubber Soles

Soles accumulate the most bacteria and debris. Give them extra attention.

• Scrub the soles using a toothbrush / soft brush and a mix of dish soap and water.
• For extra brightness, make a paste with baking soda and water.
• Let sit for a few minutes before scrubbing again.
• Rinse and dry thoroughly. For sanitation, spray a disinfectant or wipe with alcohol.

Skechers Go Walk Shoes

Skechers Go Walk shoes are designed to be machine washable:

• Remove insoles and laces first.
• Place the shoes in a mesh laundry bag to protect them during the wash.
• Use cold water and a gentle cycle in the machine.
• Do not tumble dry. Always air dry the shoes completely.

How to Sanitize Shoes

Sanitizing is especially important for nurses who work in high-risk settings like ICUs, ERs, or infectious wards.

Effective Ways:

• Use fabric-safe disinfectant sprays after each shift to kill surface germs.
• Try UV Shoe Sanitizers that use light to eliminate microbes without moisture or chemicals.
• Wipe shoes with non-bleach disinfectant wipes between deep cleans.

Want to know how to sanitize shoes fast after work? These are all quick, effective options.

How to Clean Stinky Shoes

Odor is one of the most common issues nurses face with their shoes. Let’s tackle it from the source.

Why Shoes Smell:

• Bacteria thrive in warm, moist environments—like the inside of a nurse’s shoe.
• Sweat and lack of airflow create the perfect storm.
• Not rotating or cleaning shoes regularly allows bacteria buildup.

Deodorizing Methods:

• Sprinkle baking soda inside the shoes and let sit overnight to absorb odors.
• Use deodorizing shoe inserts to keep shoes fresh between wears.
• Let shoes air out completely between shifts—avoid storing them in dark, damp lockers.

These methods are the best way to tackle how to clean stinky shoes and prevent it from returning.

How to Clean Shoe Soles

Scrubbing with soap and baking soda lifts grime and restores freshness to the dirtiest part of your shoes—your soles.

Tools:

• Old toothbrush or scrub brush
• Dish soap or gentle detergent
• Baking soda paste (for white or stained soles)

Steps:

1. Dip the brush in soapy water and scrub the sole thoroughly.
2. Rinse with warm water and wipe clean.
3. Apply baking soda paste to scuffed or stained areas.
4. Let sit 5–10 minutes, then scrub again.
5. Rinse and dry, then spray with disinfectant for extra cleanliness.

Curious how to clean shoe soles thoroughly? Scrubbing and disinfecting make the biggest difference.

How to Disinfect Used Shoes

Buying pre-owned or secondhand shoes? It’s smart—and safe—if done right.

Steps:

1. Clean outer and inner surfaces using soapy water and a brush.
2. Apply antibacterial spray inside the shoe thoroughly.
3. Let shoes air dry.
4. For extra assurance, place in a UV sterilizer for 10–15 minutes.

Now you know how to disinfect used shoes without damaging them.

Ongoing Maintenance Tips

Preventative care keeps shoes looking new and performing well.

Maintenance Schedule:

• Weekly: Light clean and deodorize.
• Monthly: Deep clean based on material.
• Daily: Sanitize after work if in high-risk areas.

Additional Tips:

• Rotate between 2–3 pairs to let shoes breathe.
• Store in a cool, dry place—avoid plastic bags or airtight bins.
• Apply water-repellent spray to guard against spills and stains.

Routine maintenance prevents buildup and keeps odors and damage at bay.

Recommended Products

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Conclusion

Knowing how to clean nursing shoes without damaging the material is more than a cleaning hack—it’s a professional necessity. Regular cleaning improves hygiene, comfort, and durability.

Treat your shoes well, and they’ll support you through every long shift.

Want options? We’ve picked out the best nursing shoes of 2025 for you

FAQs

How do I sanitize my nursing shoes daily?

Use a disinfectant spray or UV sterilizer after each shift. Both are quick and effective.

What’s the best way to clean stinky shoes?

Baking soda, deodorizing inserts, and frequent airing out.

Can you wash Skechers Go Walk shoes in a washing machine?

Yes, but only with cold water, gentle cycle, and a mesh laundry bag. Always air dry.

How do you disinfect used shoes safely?

Wash thoroughly, use antibacterial spray, and finish with UV sanitizing.

How do you clean dirty rubber soles?

Scrub with soap, rinse well, and use baking soda paste for whitening.